Background and Aim: Restoration of deepdental caries without pulp exposure is usually challenging for dentists.In order to prevent pulp exposure and subsequent root canal therapy (RCT), indirect pulp capping is usually performed.Stepwise excavation (SE) is a conservative method that canreduce the incidence of pulp exposure and maintain tooth vitali
BackgroundHIV protease inhibitor (PI)-induced inflammatory response in macrophages is a major risk factor for cardiovascular diseases.We have previously reported that berberine (BBR), a traditional herbal medicine, prevents HIV PI-induced inflammatory response through inhibiting endoplasmic reticulum (ER) stress in macrophages.We also found that HI
Hopanoids are mainly derived from bacteriohopanpolyols that occur especially in bacteria, show the importance of bacterial lipid contributions in geological materials.In this work, GC-MS and RP-HPLC-APCI-MS analyses of hopanoid biomarkers in Covers oxic and anoxic sediment samples from Lake Cadagno (Swiss Alps) and Lake Voua de la Motte (Haute Savo
Abstract Cancer-associated fibroblasts (CAFs) are the most abundant stromal components in the tumor microenvironment (TME) and closely involved in tumor progression.However, the precise biological functions and molecular mechanisms of CAFs in the TME have yet to be understood.Here, we demonstrate that WEE2-AS1 is highly expressed in the CAF-derived